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Description
PIK3CD Recombinant Rabbit mAb (SDT-1978-148)Product Specification Host Rabbit Antigen PIK3CD Synonyms Phosphatidylinositol 4,5 bisphosphate 3 kinase catalytic subunit delta isoform; PI3 kinase subunit delta; PI3K delta; PI3Kdelta; PtdIns 3 kinase subunit delta; Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta (PtdIns 3 kinase subunit p110 delta; p110delta) Immunogen Synthetic Peptide Location Cytoplasm Accession O00329 Clone Number SDT 1978 148 Antibody Type
Product Specification
| Host | Rabbit |
| Antigen | PIK3CD |
| Synonyms | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta (PtdIns-3-kinase subunit p110-delta; p110delta) |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | O00329 |
| Clone Number | SDT-1978-148 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms |
| Positive Sample | Jurkat, K562, HT-1080, moues spleen, mouse brain |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms |
| IHC-P | 1:250 | Hu, Ms |
| ICC | 1:500 | Hu |
Background
PIK3CD is a gene that encodes a protein which is an integral part of the phosphatidylinositol 3-kinase (PI3K) signaling pathway. This pathway is crucial for various cellular functions including cell growth, proliferation, survival, and metabolism. The PIK3CD protein specifically refers to the delta isoform of the catalytic subunit of PI3K. It is predominantly expressed in immune cells and plays a significant role in the regulation of immune responses. Abnormal activation or mutations in the PIK3CD gene can lead to a range of diseases including certain types of leukemia and other immune-related disorders. Understanding its function and regulation is important for developing targeted therapies in cancer and immune system disorders.
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4.5 ★★★★★
Based on 874 reviews
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Product Reviews
★★★★★ 5
noir
Format: Kindle
Always the last person you can think of is the murderer. The same with this book also. I love learning about new cultures and you can learn some things about Chinese culture from this book. So interesting
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Reviewed in the United States on September 6, 2024
★★★★★ 3
Pretty good
Format: Hardcover
In 1932, Lulu Wong made a name for herself by leaving Chinatown and becoming a Hollywood star. Most girls who look like her don't get lead roles, so Lulu is the pride of her neighborhood. So everyone is shocked when Lulu's body is found in a local stable far from her Beverly Hills home by her friends, sisters May and Gemma. The girls know that the police won't look too hard into the murder, so they decide to take matters into their own hands. As they investigate, the sisters discover a plot to frame Chinatown as a den of iniquity that should be demolished in favor of constructing a new train station. May and Gemma soon find themselves in a race against time to not only find justice for their friend but save their neighborhood, all while being targeted by a killer.
I've only read a few books by Lee, but they've all been winners. I love her style when it comes to YA historical fiction. She crafts compelling plotlines that include real issues of the time with characters you can't help but root for. I liked both our main characters. May was more logical and reserved, while Gemma was a spitfire, but they balanced each other perfectly. I liked how we got both of their POVs, but I did enjoy Gemma's slightly more because I loved her gumption. I thought the mystery was well-paced and kept me intrigued. I had no clue how it would play out, and I liked how Lee wrapped it all up. It did drag a bit in the middle, but overall, I thought it was entertaining.
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Reviewed in the United States on April 23, 2024
★★★★★ 4
not as good but nearly there
Format: Kindle
I had hoped that Kill Her Twice would grab my attention in the first few pages and not let go till the very end (like her other books I have read), but this one had a very. Slow. Start.
The mystery of the death of a young Chinese starlet in California in the early 1900’s is the catalyst that starts everything: new characters are continuously introduced, their motivations becoming clear and murky and clear again several times before the last quarter of the book. But. The last quarter (finally) had me hooked.
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Reviewed in the United States on January 1, 2025
★★★★★ 5
Excellent
Format: Hardcover
Another wonderful book by this great author. I love the stories, but also her style and her sense of humor.
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Reviewed in the United States on July 11, 2024
★★★★★ 4
YA historical murder mystery
Format: Hardcover
3.5 stars
What I Liked:
-Character voices seems to be once of Lee's writing strengths. From the start of the book, Gemma and May's voices sparkle on the pages. Gemma herself seemed to be a little stronger of a character, but I think that's because she had a more spunky, active personality.
-The positive sister relationship made me happy. So often, I feel like siblings don't appear in fiction, or if they do they just fight with each other. I liked how all of the Chow sisters worked together, and the positive family relationships in general.
What I Struggled With:
-Something about the mystery fell flat and I was left wanting more. I can't pin my finger on exactly why I felt that way, but it might have had to do with how Gemma and May solved the murder. They honestly don't really see it coming or put together many clues until the end. When the murderer revealed everything, I could see the crumbs that had been foreshadowed--but I think that they needed something /more/ to make them work.
- I'm glad that Gemma and Freddie didn't end up together. I'm not entirely sure of what the age difference was, but since he'd already graduated med school and seemed to have been a doctor for a while, I'm guessing it was fairly large. Because of the age gap, I was a little uncomfortable with the relationship that seemed to grow between them. I don't think it would have bothered me if just Gemma had a crush, but Freddie seemed to like her as well. But as I already said, they don't end up together.
Overall:
I enjoyed Kill Her Twice. But I was a little disappointed in mystery side of it. Yes, Gemma and May are solving a murder, but the mystery seemed to fall a little flat. However, Lee's abilities in writing characters shine.
Cautions: three instances of swearing; one blasphemy; light romance; one kiss; brief, moderate violence; non-descriptive mentions of poisoning; two minor characters are discovered to be gay, referenced briefly; an unmarried character is discovered to have been pregnant, which is referenced multiple times ; several Bible verses are taken out of context and twisted
(I received an eARC through NetGalley. All thoughts are my own.)
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Reviewed in the United States on November 25, 2025