Synaptotagmin-1 (SYT1) Recombinant Rabbit mAb (S-2226-76)
SKU: 112705046

Synaptotagmin-1 (SYT1) Recombinant Rabbit mAb (S-2226-76)

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Description

Synaptotagmin-1 (SYT1) Recombinant Rabbit mAb (S-2226-76)Product Specification Host Rabbit Antigen Synaptotagmin 1 (SYT1) Synonyms Synaptotagmin I (SytI); p65; SVP65; SYT Immunogen Synthetic Peptide Location Cytoplasm, Synapse Accession P21579 Clone Number S 2226 76 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu, Ms, Rt Positive Sample Mouse brain, rat brain Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40%

Product Specification


Host Rabbit
Antigen Synaptotagmin-1 (SYT1)
Synonyms Synaptotagmin I (SytI); p65; SVP65; SYT
Immunogen Synthetic Peptide
Location Cytoplasm, Synapse
Accession P21579
Clone Number S-2226-76
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Hu, Ms, Rt
Positive Sample Mouse brain, rat brain
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms, Rt

Background

Synaptotagmin-1 (SYT1) is a crucial calcium sensor protein predominantly located in the presynaptic terminals of neurons. It plays a vital role in the process of neurotransmitter release by facilitating the rapid and precise fusion of synaptic vesicles with the presynaptic membrane. When an action potential reaches the presynaptic terminal, the influx of calcium ions triggers conformational changes in SYT1, which then interacts with key components of the fusion machinery, such as SNARE proteins, to initiate the release of neurotransmitters into the synaptic cleft. This protein is essential for maintaining proper synaptic function and ensuring efficient communication between neurons in the nervous system.

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SKU: 112705046

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4.3 ★★★★★
Based on 2475 reviews
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H
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Hawaiian
New York, US
★★★★★ 4
Great shoes that are well made, lite weight, and comfortable.
Size: 12, Color: Brown
Just received my 2nd pair of shoes from Bruno Marc in a size 12. These are really lite and comfortable. It can be dressed down to be a casual shoe or dressed up with a nice suit. These run true to size so I ordered my usual size 12 and the fit was perfect. Being my 2nd pair of Bruno Marc's, I like the quality of their shoes and each shoe is described appropriately on fit and comfort. Insole of these shoes were awesome and provided soft comfort on the feet along with a slight arch support too. Will definitely consider ordering more Bruno Marc shoes in the future.
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Reviewed in the United States on March 11, 2025
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JCMIV63
Chelsea, US
★★★★★ 5
Cushioned, comfortable, stylish and a rubber sole!
Size: 10, Color: Brown
These shoes check multiple boxes for me, comfortable, cushioned, rubber sole and stylish. As my feet grow old and worn out, I'm on a constant search for comfortable, cushioned shoes that are suitable for work and dressier occasions. I have tried many expensive shoes that look great but either lack cushioning, arch support and or comfort. One of the nice things is these shoes have a rubber sole, where most cushioned shoes have the foam soles which are great, but they tend to lack grip particularly when its damp/wet. They have average arch support, but the insole is removable and I put my own cushioned arch support. Love these!
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Reviewed in the United States on April 6, 2026
D
Verified Purchase
DDD Projects
Massapequa, US
★★★★★ 5
OG Style
I am a big fan of Bruno Marc shoes. Over the years they have provided comfortable and affordable boots and shoes. These blue, tan and white soled dress sneakers are no exception. They have a nice finished look that makes them both causal and dressy. The lightweight style is still warm enough for colder mid-west winters. The box of the toes is wide and comfortable. The insole is well padded and a pleasure to wear. This is another fine pair of shoes to add to my collection and yours.
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Reviewed in the United States on January 14, 2026
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Premium Reviews
Draper, US
★★★★★ 5
Must buy: Comfort + Casual + Well Made / Ventilated
Size: 8, Color: Brown
Just buy it! I have put in roughly 15,000 steps in this shoes in 10 days and I can't believe how comfortable they are after this much rough use in short amount of time. I highly recommend this shoes to anyone looking for comfort in casual style.
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Reviewed in the United States on May 4, 2026
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William W.
Bozeman, US
★★★★★ 5
WIDE Dress Shoes With SUPPORT
Size: 10.5, Color: Brown
I've seen dress shoes and worn dress shoes before, but these are simply the best dress shoes I've ever worn my entire life. 99% of dress shoes have the same problem, they have the thinnest little soles that offer no support. BRUNO MARC HAS SOLVED THE PROBLEM. These dress shoes not only support wide feet like mine who historically have had and still have little support in the market, but Bruno Marc has wide options that fit perfectly, and the support with the thick foam sole is so needed and awesome. I had a pleasant surprise putting these things on and there being some tactile grip enhancers inside the shoe so you can feel the shoes better and get a little tickle / massage while you're at it. These things are dripping with style, easy to wear, and while they might look firm on the outside, on the inside the shoe just has such a nice flexibility and foamy feel, the top where the top of your feet feel the roof of the shoe, it has such perfect ooey gooey support I can't believe it. The outside sole also has this neat tactile feel. The durability looks good and feels good for now.
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Reviewed in the United States on September 28, 2025

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