Core Nutritionals 5-AT
SKU: 19773956515

Core Nutritionals 5-AT

Sale price$31.49 Regular price$34.99
Save 10%

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Jul 4 - Jul 9

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

Core Nutritionals 5-AT5 Etioallocholen 3b,7b,17b triol: More commonly known as androstenetriol, 5 etioallocholen 3 beta 7 beta 17beta triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex

5-Etioallocholen-3b,7b,17b-triol: More commonly known as androstenetriol, 5-etioallocholen-3 beta-7 beta-17beta-triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex steroids such as testosterone and estrogen, up-regulating (increasing) immune response and countering the immunosuppressive actions of corticosteroids, and maybe the most impressive, directly and strongly suppressing the release of cortisol itself!

Though DHEA’s properties have been well-established and understood for decades, derivatives and metabolites of DHEA have more recently been the subject of research in animals and humans – demonstrating effects that are, at times, many orders of magnitude more significant than the parent compound (up to 100x as potent!).

Like DHEA, cortisol is one of the body’s most abundant and important endogenous steroids. While detailing in full the expansive list of cortisol’s functions is impossible, we can generally say that cortisol’s role in the human body is to break down bodily tissue and nutrients for the purpose of energy provision (to be catabolic), to act as an immunosuppressive, and to regulate blood sugar. Cortisol fulfills these functions by inducing gluconeogenesis (the breakdown of non-glucose intermediates, such as amino acids in muscle tissue, into glucose) and glycogenolysis (the breakdown of glycogen into glucose), inhibiting peripheral glucose utilization, and inhibiting cell lines critical to the body’s immune response.

In less complex terms, we can simply say that cortisol is responsible for inhibiting many of the processes that we as fitness enthusiasts want to start, and for starting many of the processes that we want to inhibit. Cortisol plays a role in:

1. Preventing our muscle cells from uptaking glucose (inducing insulin resistance).
2. Preventing muscle protein synthesis.
3. The breakdown of glycogen (the compound responsible for that “full look”).
4. Suppressing the immune processes involved in muscle growth.

While these are necessary functions, their overexpression is precisely the opposite of what we want – in fact, certain trials in humans have shown that an increase in plasma cortisol within the physiologic range increases proteolysis (breakdown of proteins) and degrades whole body amino acid synthesis! That is bad, bad news.

Enter DHEA and its metabolite, androstenetriol: In emerging animal literature, both androstenetriol and its metabolites have been shown to possess very potent anti-glucocorticoid activity – remembering that cortisol is the parent compound for this group – and anti-immunosuppressive actions in a number of different tissue types. In fact, androstenetriol is one of the most potent anti-glucocorticoids the body produces – exerting almost unbelievable effects in certain pro-inflammatory cell lines.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 19773956515

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.4 ★★★★★
Based on 1228 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
H
Verified Purchase
Heymi
Los Angeles, US
★★★★★ 5
Empowered Health With a Trusted Daily Tonic
Size: 2 Fl Oz (Pack of 1), Style: Seed Oil
🌿 Key Highlights 1. Clean, high-quality formulation This oil is cold-pressed, preserving all the natural thymoquinone and antioxidants, as confirmed on the brand site  . It’s also GMP-certified and hexane-free, and includes a thoughtfully curated blend of vitamins D3 and K2—perfect for bone, joint, and immune support. () 2. Noticeable health improvements Customers report energy boosts, improved digestion, reduced stress, and joint relief. One reviewer mentioned “lower blood pressure, better sleep, reduced anxiety, and even 17 lbs lost” . Another said their nails and skin “are in their best shape.”  3. Versatile and easy to take The dropper makes dosing simple—1 ml once or twice daily. I mix it in smoothies or take it straight, followed by water. It’s also applied topically for skin hydration and healing.  ⸻ ✅ Pros + Cons 👍 Pros: • Pure, high-potency oil with added nutrients—value-packed • Tangible benefits: energy, digestion, mood, stress • Fortified blend supports skin, immune, bone health • Amazon reviews show high satisfaction (4.8★ from 195 users)   👎 Cons: • Strong herbal taste—some users mask it with water or tea () • Small bottle (2 oz)—plan for regular use ⸻ 💡 Pro Tips for Users • Start with 1 dropper/day to assess tolerance, then increase. • Use a permanent marker to jot the start date for easier tracking. • Store in a cool, dark place—cold pressing makes it sensitive to heat/light. ⸻ 🏆 Final Take GuruNanda Black Seed Oil offers a powerful, multi-benefit approach in a single bottle. Between its purity, nutrient boost, and real-world effects—from energy and immunity to digestion and joint comfort—it’s earned a permanent spot in my daily routine. Whether you’re seeking holistic wellness or functional support, this is a smart, effective addition to your shelf. Highly recommended!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 14, 2025
H
Verified Purchase
harvardleb
New York, US
★★★★★ 5
Taste ok, better than a pill, and best for joints
Size: 2 Fl Oz (Pack of 1), Style: Seed Oil
I’ve been taking this for more than a year and was great for my joints. It also kept my vitamin d consistent. The taste is bearable, anything better than a large pill
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 3, 2026
M
Verified Purchase
Michelle George
Dallas, US
★★★★★ 5
Great wellness addition
Size: 2 Fl Oz (Pack of 1), Style: Seed Oil
Good quality oil and easy to incorporate into my routine. Packaging was nice and the product feels fresh and well made.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 11, 2026
J
Verified Purchase
Jessica Reviere
Grantham, US
★★★★★ 4
Worked for me
Size: 2 Fl Oz (Pack of 1), Style: Seed Oil
Been taking this for a year now..I usually get sick a few times a year but didn't even catch a cold last winter. So this must be doing great for my immune system..the taste is a little bit harsh but after months of taking it the taste really dosent bother me anymore. I gave it a four because I originally got it for energy but I didn't really see improvement in that area but that could have just been something else off with me. Definitely will keep buying this
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 9, 2025
S
Verified Purchase
Sr
Carnegie, US
★★★★★ 5
So versatile
Size: 2 Fl Oz (Pack of 1), Style: Seed Oil
I can't express how much I love this tooth pain? Right on the tooth dry skin? Slather on as a carrier oil with castor oil no tanning oil? Put it on tan in 30 mins no burn joint pain? take twice a day I can't live with out this oil! it's honestly a god send thank you so much guru nanda been using for 3 years consistently for everything
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 27, 2026

recommand products